Abstract Efficient cytosolic delivery of RNA molecules remains a formidable barrier for RNA therapeutic strategies. Lipid nanoparticles (LNPs) serve as state-of-the-art carriers that can deliver RNA molecules intracellularly. as exemplified by the recent implementation of several vaccines against SARS-CoV-2. Using a bottom-up rational design approach. https://www.ealisboa.com/super-find-2009-2014-Dodge-Ram-1500-4pc-Bolt-on-Rivet-Style-Spyder-Fender-Flares-hot-value/