Q: Is there any contraindication using Conolidine if having Jantovan, blood thinner. thank you.. A: There is restricted info on contraindications concerning Conolidine and blood thinners like Jantovan. Though the opiate receptor depends on G protein coupling for signal transduction, this receptor was observed to benefit from arrestin activation https://whatischronicpain65421.tribunablog.com/detailed-notes-on-conolidine-46646299