The neurologic phenotype in SCA8 BAC expansion although not BAC Management strains demonstrated the pathogenicity of the (CTG-CAG)n expansion. Additionally, the expression of noncoding (CUG)n enlargement ATXN8OS transcripts and the discovery of intranuclear polyglutamine inclusions proposed that SCA8 pathogenesis consists of poisonous attain-of-function mechanisms at equally the prote... https://louisxdinp.humor-blog.com/27781617/about-isa-2011b